Inactivation of Rho-GTP by p190RhoGAP
收藏reactome.org2025-03-25 收录
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p190RhoGAP complexed with Plexin-B1 stimulates GTP hydrolysis by RhoA. The resulting lower levels of Rho-GTP may account for F-actin depolymerization and cytoskeletal rearrangements.
p190RhoGAP与Plexin-B1复合物相互作用,可刺激RhoA的GTP水解。由此产生的Rho-GTP水平降低可能解释了F-肌动蛋白的解聚和细胞骨架的重排。
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