CRYSTAL STRUCTURE OF YEAST THYMIDYLATE KINASE COMPLEXED WITH THE BISUBSTRATE INHIBITOR TP5A AT 2.0 A RESOLUTION: IMPLICATIONS FOR CATALYSIS AND AZT ACTIVATION
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CRYSTAL STRUCTURE OF YEAST THYMIDYLATE KINASE COMPLEXED WITH THE BISUBSTRATE INHIBITOR TP5A AT 2.0 A RESOLUTION: IMPLICATIONS FOR CATALYSIS AND AZT ACTIVATION Descriptor: P1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE, THYMIDYLATE KINASE Authors: Lavie, A, Schlichting, I, Konrad, M, Goody, R.S, Brundiers, R, Reinstein, J. Deposit date: 1998-01-26 Release date: 1999-02-16 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5'-adenosyl) P5-(5'-thymidyl) pentaphosphate (TP5A) at 2.0 A resolution: implications for catalysis and AZT activation. Biochemistry, 37, 1998
分辨率2.0埃的酵母胸苷酸激酶(thymidylate kinase)与双底物抑制剂TP5A复合物的晶体结构：对催化反应与齐多夫定(AZT)激活机制的启示
Descriptor: P1-(5'-腺苷基)P5-(5'-胸苷基)五磷酸、胸苷酸激酶(thymidylate kinase)
Authors: Lavie, A、Schlichting, I、Konrad, M、Goody, R.S、Brundiers, R、Reinstein, J
Deposit date: 1998年1月26日
Release date: 1999年2月16日
Last modified: 2024年5月22日
Method: X射线衍射(2埃)
Cite: 酵母胸苷酸激酶与双底物抑制剂P1-(5'-腺苷基)P5-(5'-胸苷基)五磷酸(TP5A)复合物的2.0埃分辨率晶体结构：对催化反应与AZT激活的启示。《生物化学》(Biochemistry)，第37卷，1998年
创建时间：
1998-01-26
