Effect of Pterostilbene (PTE) treatment on gene expression after intracerebral hemorrhage injury

To investigate the effect of Pterostilbene(PTE) on gene expression after intracerebral hemorrhage injury, we employed RNA sequencing (RNA-seq) to profile the mRNA expression ensuing PTE treatment after ICH. Different gene distribution could be clearly seen on the volcano plot between diferent comparisions among Sham, ICH, and ICH+PTE group. Finally, we showed that 1021 shared genes overlapping between those differentially expressed genes, which was reversed by PTE treatment Experimental mice were randomly and equally divided into three groups: sham group, ICH group, ICH + PTE group. At 3 days after diferent treatments, 3 mice were randomly selected from each group and used to preform RNA sequencing.