The purpose of this study was to determine gene expression changes in hematopoietic stem cells (HSCs) in young and old BALB/c mice, and the impact of Sirt1 gene knockout on HSC aging. Hematopoietic St
Bayesian optimal design is considered for experiments where the response distribution depends on the solution to a system of nonlinear ordinary differential equations. The motivation is an experiment
Mammalian aging is associated with multiple defects of hematopoiesis, most prominently with the impaired development of T and B lymphocytes. This defect is thought to originate in hematopoietic stem c
