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RNA-seq analysis identifies gene expression profile in rat ANK-deficiency VSMCs

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To obtain deeper insight into the underlying mechanisms linking ANK to the pathogenesis of AA, high-throughput RNA-sequencing of ANK-deficient rat VSMCs via small interfering RNA was performed. A total of 972 upregulated differentially expressed genes (DEGs) were identified in ANK-deficient rat VSMCs, and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis presented several pathways highly related to inflammation and energy metabolism

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