Psilocybin, and other serotonergic psychedelics, have re-emerged as therapeutics for neuropsychiatric disorders, including addiction. Psilocybin induces long-lasting effects on behavior, likely due to
Data presented as mean ± SD, unless otherwise noted. *Dopamine agonists included pramipexole, ropinirole, pergolide and bromocriptine. ^Other medications included amantadine, trihexyphenidyl, and benz
3,4-Methylenedioxymethamphetamine (MDMA, ‘ecstasy') and methylphenidate are widely used psychoactive substances. MDMA primarily enhances serotonergic neurotransmission, and methylphenidate increases d
Data are shown mean (standard deviation). CPZeq: chlorpromazine equivalent of total antipsychotics.IQ: Intelligence Quotient, PANSS: Positive and Negative Symptom Scale.
This supplementary appendix reports the original protocol and additional analyses of the network meta-analysis published on World Psychiatry with the following title: Ostuzzi G,...