Magnetoelncephalography (MEG) recordings from a phantom with Deep Brain Stimulation (DBS) artefacts

This dataset was acquired in an experiment aimed at testing the effects of Deep Brain Stimulation (DBS) artefacts on MEG recordings using MEG phantom. The experimental procedures are described and the results are reported in the following publication: Oswal A, Jha A, Neal S, Reid A, Bradbury D, Aston P, Limousin P, Foltynie T, Zrinzo L, Brown P, Litvak V. Analysis of simultaneous MEG and intracranial LFP recordings during Deep Brain Stimulation: a protocol and experimental validation. J Neurosci Methods. 2016 Mar 1;261:29-46. doi: 10.1016/j.jneumeth.2015.11.029. Epub 2015 Dec 14. We tested different combinations of presence of ferromagnetic connection wires, movements designed to emulate breathing and heart-beat related artefacts in real patients (see paper for details) and DBS which could be bipolar (only inducing weak artefacts) and monopolar (inducing severe artefacts). We tested 3 stimulation frequencies: 5Hz, 20Hz and 130Hz The datasets included here are as follows: phantom090715_BrainampDBS_20150709_01.ds.zip -wires+ , movement-, stimulation-phantom090715_BrainampDBS_20150709_02.ds.zip - wires- , movement-, stimulation- %This is a clean dataset that can be used as a referencephantom090715_BrainampDBS_20150709_03.ds.zip - wires- , movement-, stimulation+130Hz monopolarphantom090715_BrainampDBS_20150709_04.ds.zip - wires- , movement+, stimulation+130Hz monopolarphantom090715_BrainampDBS_20150709_05.ds.zip - wires- , movement-, stimulation+130Hz monopolarphantom090715_BrainampDBS_20150709_06.ds.zip - wires+ , movement-, stimulation+130Hz monopolarphantom090715_BrainampDBS_20150709_07.ds.zip - wires+ , movement+, stimulation+130Hz monopolar %This is the most realistic dataset for clinical frequency DBSphantom090715_BrainampDBS_20150709_08.ds.zip - wires+ , movement+, stimulation-phantom090715_BrainampDBS_20150709_09.ds.zip - wires+ , movement-, stimulation+20Hz monopolarphantom090715_BrainampDBS_20150709_10.ds.zip - wires+ , movement-, stimulation+5Hz monopolarphantom090715_BrainampDBS_20150709_11.ds.zip - wires+ , movement+, stimulation+5Hz monopolarphantom090715_BrainampDBS_20150709_12.ds.zip - wires+ , movement+, stimulation+20Hz monopolarphantom090715_BrainampDBS_20150709_13.ds.zip - wires+ , movement+, stimulation+130Hz bipolarphantom090715_BrainampDBS_20150709_14.ds.zip - wires+ , movement+, stimulation+20Hz bipolarphantom090715_BrainampDBS_20150709_15.ds.zip - wires+ , movement+, stimulation+5Hz bipolarphantom090715_BrainampDBS_20150709_16.ds.zip - wires- , movement+, stimulation+20Hz monopolarphantom090715_BrainampDBS_20150709_17.ds.zip - wires- , movement+, stimulation+5Hz monopolarphantom090715_BrainampDBS_20150709_18.ds.zip - wires- , movement-, stimulation+5Hz monopolarphantom090715_BrainampDBS_20150709_20.ds.zip - wires- , movement-, stimulation+20Hz monopolar phantom.mov - movie showing the phantom movementreadme.txt - this file The MEG datasets also have accompanying BrainVision data sets where a copy of the 27 Hz sinusoid waveform fed to the phantom 'brain' source was stored. Since these are not required for testing artefact removal methods and using them would require merging with MEG we do not share them here but they could be provided on request. This work was supported by the Medical Research Council and the National Institute for Health Research University College London Hospitals Biomedical Research Centre.The UK MEG community is supported by Medical Research Council grant MR/K005464/1. The Wellcome Trust Centre for Neuroimaging is supported by core funding from the Wellcome Trust 091593/Z/10/Z. Please contact Vladimir Litvak [e-mail] for any additional information本数据集源自一项实验，旨在探究脑深部刺激（Deep Brain Stimulation, DBS）伪迹对脑磁图（Magnetoencephalography, MEG）记录的影响，实验采用脑磁图仿真头模（MEG phantom）开展。实验流程与实验结果已发表于以下学术论文：Oswal A, Jha A, Neal S, Reid A, Bradbury D, Aston P, Limousin P, Foltynie T, Zrinzo L, Brown P, Litvak V. 《脑深部刺激期间同步采集的脑磁图与颅内局部场电位（Local Field Potential, LFP）记录分析：实验方案与验证》，*Journal of Neuroscience Methods*（《神经科学方法学杂志》），2016年3月1日，第261卷：29-46页。DOI: 10.1016/j.jneumeth.2015.11.029，2015年12月14日在线发表。 本实验测试了多种组合条件，包括铁磁连接导线的有无、模拟真实患者呼吸与心跳相关伪迹的肢体运动、以及两种类型的脑深部刺激：双极刺激（仅产生微弱伪迹）与单极刺激（可产生严重伪迹）。实验共设置3种刺激频率：5Hz、20Hz与130Hz。 本次公开的数据集详情如下： 1. phantom090715_BrainampDBS_20150709_01.ds.zip：存在铁磁连接导线，无肢体运动，施加脑深部刺激 2. phantom090715_BrainampDBS_20150709_02.ds.zip：无铁磁连接导线，无肢体运动，施加脑深部刺激【注：本数据集为无伪迹的对照数据集，可作为参考基准】 3. phantom090715_BrainampDBS_20150709_03.ds.zip：无铁磁连接导线，无肢体运动，施加130Hz单极刺激 4. phantom090715_BrainampDBS_20150709_04.ds.zip：无铁磁连接导线，存在肢体运动，施加130Hz单极刺激 5. phantom090715_BrainampDBS_20150709_05.ds.zip：无铁磁连接导线，无肢体运动，施加130Hz单极刺激 6. phantom090715_BrainampDBS_20150709_06.ds.zip：存在铁磁连接导线，无肢体运动，施加130Hz单极刺激 7. phantom090715_BrainampDBS_20150709_07.ds.zip：存在铁磁连接导线，存在肢体运动，施加130Hz单极刺激【注：本数据集为贴合临床刺激频率的最真实模拟数据集】 8. phantom090715_BrainampDBS_20150709_08.ds.zip：存在铁磁连接导线，存在肢体运动，未施加脑深部刺激 9. phantom090715_BrainampDBS_20150709_09.ds.zip：存在铁磁连接导线，无肢体运动，施加20Hz单极刺激 10. phantom090715_BrainampDBS_20150709_10.ds.zip：存在铁磁连接导线，无肢体运动，施加5Hz单极刺激 11. phantom090715_BrainampDBS_20150709_11.ds.zip：存在铁磁连接导线，存在肢体运动，施加5Hz单极刺激 12. phantom090715_BrainampDBS_20150709_12.ds.zip：存在铁磁连接导线，存在肢体运动，施加20Hz单极刺激 13. phantom090715_BrainampDBS_20150709_13.ds.zip：存在铁磁连接导线，存在肢体运动，施加130Hz双极刺激 14. phantom090715_BrainampDBS_20150709_14.ds.zip：存在铁磁连接导线，存在肢体运动，施加20Hz双极刺激 15. phantom090715_BrainampDBS_20150709_15.ds.zip：存在铁磁连接导线，存在肢体运动，施加5Hz双极刺激 16. phantom090715_BrainampDBS_20150709_16.ds.zip：无铁磁连接导线，存在肢体运动，施加20Hz单极刺激 17. phantom090715_BrainampDBS_20150709_17.ds.zip：无铁磁连接导线，存在肢体运动，施加5Hz单极刺激 18. phantom090715_BrainampDBS_20150709_18.ds.zip：无铁磁连接导线，无肢体运动，施加5Hz单极刺激 19. phantom090715_BrainampDBS_20150709_20.ds.zip：无铁磁连接导线，无肢体运动，施加20Hz单极刺激 20. phantom.mov：展示脑磁图仿真头模运动的视频文件 21. readme.txt：本说明文件 本次公开的脑磁图数据集还配套有BrainVision数据集（BrainVision data set），其中存储了输入至仿真头模“脑部”信号源的27Hz正弦波形数据。由于该配套数据无需用于伪迹去除方法的测试，且需与脑磁图数据合并后方可使用，因此本次未公开该数据集，但若有需求可另行提供。 本研究获得了医学研究理事会（Medical Research Council）与英国国民保健制度研究学院伦敦大学学院医院生物医学研究中心的资助。英国脑磁图社区的相关工作得到了医学研究理事会项目MR/K005464/1的支持。惠康信托神经影像中心的运营获得了惠康信托基金核心资助091593/Z/10/Z。如需获取更多信息，请联系弗拉基米尔·利特瓦克（Vladimir Litvak），电子邮箱：[e-mail]。