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Robustness of selective and demographic inference in African American dataset.

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NIAID Data Ecosystem2026-03-06 收录
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Left column: MLE and approximate 95% confidence limits of demographic and selection parameter estimates for the full model. Center columns: MLE using folded site-frequency spectra (ΔLLsil = 1.89 and ΔLLrepl = 1.81 between folded MLE and full MLE) and using full site-frequency spectra excluding singletons (i.e., derived frequency = 1 or n−1: ΔLLsil = 2.41 and ΔLLrepl = 0.0 between no-singleton MLE and full MLE). Right column: MLE assuming silent sites are under weak purifying selection (γ = −1).

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2008-05-30
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