Crystal structure of Tryptophan Synthase from Salmonella typhimurium with 2-aminophenol quinonoid in the beta site and the F6 inhibitor in the alpha site
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Crystal structure of Tryptophan Synthase from Salmonella typhimurium with 2-aminophenol quinonoid in the beta site and the F6 inhibitor in the alpha site Descriptor: 1,2-ETHANEDIOL, 2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL DIHYDROGEN PHOSPHATE, DI(HYDROXYETHYL)ETHER, ... Authors: Hilario, E, Niks, D, Dunn, M.F, Mueller, L.J, Fan, L. Deposit date: 2013-05-06 Release date: 2014-01-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Allostery and substrate channeling in the tryptophan synthase bienzyme complex: evidence for two subunit conformations and four quaternary states. Biochemistry, 52, 2013
鼠伤寒沙门氏菌(Salmonella typhimurium)色氨酸合酶(Tryptophan Synthase)的晶体结构,其β位点结合2-氨基苯酚醌型中间体(2-aminophenol quinonoid),α位点结合F6抑制剂(F6 inhibitor)。描述符:1,2-乙二醇(1,2-ETHANEDIOL)、二氢磷酸2-{[4-(三氟甲氧基)苯甲酰基]氨基}乙酯(2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL DIHYDROGEN PHOSPHATE)、二(羟乙基)醚(DI(HYDROXYETHYL)ETHER)…… 作者:Hilario, E、Niks, D、Dunn, M.F、Mueller, L.J、Fan, L。提交日期:2013年5月6日,发布日期:2014年1月1日,最后修改日期:2023年9月20日。实验方法:X射线衍射(X-RAY DIFFRACTION,分辨率1.77埃)。引用文献:《色氨酸合酶双酶复合物中的别构效应与底物通道:两种亚基构象与四种四聚体状态的证据》,《生物化学(Biochemistry)》,第52卷,2013年
创建时间:
2013-05-06



