In Vitro and in Vivo Combinations of Cefotaxime and Minocycline against Aeromonas hydrophila

Name: In Vitro and in Vivo Combinations of Cefotaxime and Minocycline against Aeromonas hydrophila
Creator: American Society for Microbiology (ASM)
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PubMed Central2026-05-16 收录

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https://pmc.ncbi.nlm.nih.gov/articles/PMC90456/

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The activities of cefotaxime and minocycline against Aeromonas hydrophila were investigated. Cefotaxime (4 times the MIC) plus minocycline (0.75 times the MIC) elicited an inhibitory effect for 48 h in a time-kill study, and more infected mice treated with both drugs survived (91%) than survived after treatment with cefotaxime (9%) or minocycline (44%) alone, suggesting that cefotaxime and minocycline act synergistically against A. hydrophila.

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American Society for Microbiology (ASM)