Extended NHERF1 PDZ2 domain in complex with the PDZ-binding motif of CFTR
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Extended NHERF1 PDZ2 domain in complex with the PDZ-binding motif of CFTR Descriptor: Na(+)/H(+) exchange regulatory cofactor NHE-RF1,Cystic fibrosis transmembrane conductance regulator Authors: Martin, E.R, Ford, R.C, Robinson, R.C. Deposit date: 2019-05-16 Release date: 2020-02-05 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.2 Å) Cite: In vivocrystals reveal critical features of the interaction between cystic fibrosis transmembrane conductance regulator (CFTR) and the PDZ2 domain of Na+/H+exchange cofactor NHERF1. J.Biol.Chem., 295, 2020
与囊性纤维化跨膜传导调节因子(CFTR,Cystic fibrosis transmembrane conductance regulator)的PDZ结合基序(PDZ-binding motif)结合的延伸型NHERF1 PDZ2结构域(NHERF1 PDZ2 domain)复合物
描述:钠氢交换调节辅因子NHE-RF1(Na(+)/H+ exchange regulatory cofactor NHE-RF1)
作者:Martin, E.R、Ford, R.C、Robinson, R.C
提交日期:2019-05-16
发布日期:2020-02-05
最后修改日期:2024-01-24
实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.2埃(2.2 Å)
引用文献:体内晶体揭示了囊性纤维化跨膜传导调节因子(CFTR)与钠氢交换辅因子NHERF1的PDZ2结构域之间相互作用的关键特征。《生物化学杂志》(J.Biol.Chem.),295卷,2020年
创建时间:
2019-05-16



