Immuno-histochemistry results with type-specific anti-E4 antibodies on cervical biopsies.

HPV-16, HPV-18, and HPV-58 containing raft controls were positive with the appropriate anti-E4 antibodies in each experiment.− = negative;+ = positive.WTS-PCR = whole tissue section PCR.N/A = Not applicable (Tissues section not tested).*58 positive area is different to the area sampled by LCM (laser capture micro-dissection).**31 positive area lost from slide during immunostaining protocol.***differentiated layers lost from slide during immunostaining protocol.() = weakly positive for this type.CIN: cervical intraepithelial neoplasia.£All HPV types were detected by LCM-PCR as single type HPV infections in different CIN lesion areas.