Acute supplementation of beta-hydroxybutyrate increases visual cortical excitability in humans: a combined Electro-EncephaloGraphy and – Magnetic Resonance Spectroscopy study

1_Demographics_PlasmaLevels.csvparticipant-level demographic and physiological data: Demographics: sex and age of each participant. Metabolic measurements: plasma levels of βHB, glucose, insulin, c-peptide, glucagon and GLP1, measured at baseline and after 60, 120, and 180 minutes from the acute β-hydroxybutyrate (βHB) oral supplementation. 2_MRS.csvMagnetic Resonance Spectroscopy (MRS) results from the MEGA-PRESS sequence: Alpha-corrected GABA+ and glutamate concentrations measured before (pre) and after (post) acute βHB supplementation. 3_EEG_SteadyStateVisualEvokedPotentials.csvSteady-State Visual Evoked Potential amplitudes (second harmonic of the EEG response measured by the OZ electrode): Responses to an individual grating, before (pre) and after (post) acute βHB supplementation. Responses to the same grating superimposed with an orthogonal mask, before (pre) and after (post) acute βHB supplementation. 4_EEG_RestingState.csvEEG resting-state with eyes open: Amplitude of the resting-state EEG signal in the theta, alpha and beta ranges, each measured before (pre) and after (post) acute βHB supplementation, in three regions of interest: the individual OZ electrode, PO electrodes (PO8, PO3, PO4) and FC electrodes in frontal and central regions (Pz, Cz, Fz).