CK2:FACT phosphorylates TP53

This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>

本事件系通过计算推断自另一物种已验证的事件。推断过程基于PANTHER的同源映射。概而言之，对于所有涉及的物理实体（包括输入、输出和催化剂）均存在映射同源/同源物的反应（对于复合体而言，至少75%的组成部分必须进行映射），则将这些反应推断至另一物种。同时，对这些事件也进行高级别事件的推断，以便于更便捷的导航。有关Reactome中事件推断的更多细节和注意事项，请参阅<a href='/electronic_inference_compara.html' target = 'NEW'>此处</a>。关于PANTHER的详细信息，请参阅<a href='http://www.pantherdb.org/about.jsp' target='NEW'>此处</a>。