Crystal Structure of RPA70N in complex with 5-(4-((4-(5-carboxyfuran-2-yl)phenylthioamido)methyl)phenyl)-1-(3,4-dichlorophenyl)-1H-pyrazole-3-carboxylic acid

Crystal Structure of RPA70N in complex with 5-(4-((4-(5-carboxyfuran-2-yl)phenylthioamido)methyl)phenyl)-1-(3,4-dichlorophenyl)-1H-pyrazole-3-carboxylic acid Descriptor: 5-{4-[({[4-(5-carboxyfuran-2-yl)phenyl]carbonothioyl}amino)methyl]phenyl}-1-(3,4-dichlorophenyl)-1H-pyrazole-3-carboxylic acid, Replication protein A 70 kDa DNA-binding subunit Authors: Feldkamp, M.D, Waterson, A.G, Kennedy, J.P, Patrone, J.D, Pelz, N.F, Frank, A.O, Vangamudi, B, Sousa-Fagundes, E.M, Rossanese, O.W, Fesik, S.W, Chazin, W.J. Deposit date: 2014-08-19 Release date: 2014-11-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.28 Å) Cite: Diphenylpyrazoles as replication protein a inhibitors. ACS Med Chem Lett, 6, 2015

RPA70N与5-(4-((4-(5-羧基呋喃-2-基)苯基硫代酰胺基)甲基)苯基)-1-(3,4-二氯苯基)-1H-吡唑-3-羧酸复合物的晶体结构
描述项：5-{4-[({[4-(5-羧基呋喃-2-基)苯基]硫代羰基}氨基)甲基]苯基}-1-(3,4-二氯苯基)-1H-吡唑-3-羧酸，复制蛋白A 70kDa DNA结合亚基
作者：Feldkamp, M.D.、Waterson, A.G.、Kennedy, J.P.、Patrone, J.D.、Pelz, N.F.、Frank, A.O.、Vangamudi, B.、Sousa-Fagundes, E.M.、Rossanese, O.W.、Fesik, S.W.、Chazin, W.J.
沉积日期：2014-08-19
发布日期：2014-11-19
最后修改时间：2023-09-20
实验方法：X射线衍射（分辨率1.28 Å）
引用文献：二苯基吡唑类作为复制蛋白A抑制剂。《ACS药物化学快报》，6卷，2015年