The WGBS and ATAC-seq from human serum and amniotic cell

we constructed a genome-wide DNA methylation landscape of adult 47XXY males from blood, and ATAC-seq from amniotic cell We use three 47, XXY blood samples, three 46, XX and three 46, XY blood samples with the similar ages (20-year-old) for the DNA extraction for the further WGBS analysis. We selected two amniotic fluid cells with a karyotype identified as 47, XXY. The two 46, XY samples and two 46, XX samples were selected as the control groups.