Renal phenotype of male Akita mice by genetic background.
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NR: not reported, ND: Not detected,*Compared to strain matched non-diabetic controls,†Animal models of diabetic complications consortium (ADMCC) criteria: >10-fold increase in albuminuria, >50% decrease in GFR over the lifetime of the animal, Advanced mesangial expansion, Arteriolar hylanosis, >50% increase in GBM thickness, Tubulointerstitial fibrosis,**variable (see text for discussion),‡Increased BUN at 30–40 weeks of age, References: [3], [4], [5], [13], [30], [35], [48].
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2015-12-02



