Mean pairwise unweighted UniFrac distance for subsets of samples.

Mean pairwise unweighted UniFrac distance reflecting (A) sample-to-sample variation among replicates (left), within individuals over time (center), and between individuals (right), and (B) the average month-to-month intraindividual variation (distances between samples spanning one month) within Bangladeshi children (left) and within U.S. children (right). In A, the replicates from all six Bangladeshi adults and U.S. child 10 M were included in the analysis (Table 1). In all others (A and B), UniFrac distance calculations excluded the two additional Bangladeshi children (BK) and the Bangladeshi adult (BA) subjects because only one sample was collected from each of these individuals (Table 1). Means are shown ± SEM, and p-values were calculated by a two-tailed t-test with unequal variance.