Group transport studies of NSAIDs across PBMEC/C1-2 and ECV304.

*CF = carboxyfluorescein, n.a. = not added due to experimental or analytical reasons. Summary of permeability data of group transport studies with NSAIDs piroxicam, ibuprofen, meloxicam, tenoxicam, diclofenac and celecoxib across PBMEC/C1-2 as well as ECV304 cell layers. In each transport study the two permeability markers diazepam and carboxyfluorescein were applied at the same time. The permeability of different group compositions (all, without celecoxib, without celecoxib and carboxyfluoresein, without meloxciam), in different transport media (all, serum-free medium, glioma-conditioned medium) and the added transporter inhibitors (without meloxciam with probenecid, without meloxicam with verapamil) was measured (n = 3, data are presented as means ± SD).