Binding affinities of the tested compounds towards human MT1 and MT2 expressed in CHO cells.
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a%Resp – Percentage responses of the melatonin (MT)-mediated displacement of radioligand binding.bSelectivity was defined as the ratio Ki(MT1)/Ki(MT2).cNSB – no specific binding for up to 30 µM of tested compounds in the binding buffer.The pIC50 and %Resp were mean ± SEM of 3–5 trials done in duplicates. The corresponding Ki values were calculated using the mean pIC50 values.Binding affinities of the tested compounds towards human MT1 and MT2 expressed in CHO cells.
创建时间：
2015-12-02
