Crystal structure of the 1st SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide (aa 378-393) from human RIN3

Crystal structure of the 1st SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide (aa 378-393) from human RIN3 Descriptor: CD2-associated protein, Ras and Rab interactor 3, SULFATE ION Authors: Rouka, E, Simister, P.C, Janning, M, Kirsch, K.H, Krojer, T, Knapp, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Feller, S.M, Structural Genomics Consortium (SGC) Deposit date: 2014-09-04 Release date: 2015-08-19 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3). J.Biol.Chem., 290, 2015

人类CD2相关蛋白（CD2-associated protein, CD2AP，又称CMS）的首个SH3（Src Homology 3）结构域，与人类RIN3（Ras and Rab interactor 3, RIN3）的富脯氨酸肽段（氨基酸378-393）结合形成复合物的晶体结构。
描述：CD2相关蛋白、Ras与Rab互作蛋白3、硫酸根离子（SULFATE ION）
作者：Rouka, E、Simister, P.C、Janning, M、Kirsch, K.H、Krojer, T、Knapp, S、von Delft, F、Arrowsmith, C.H、Edwards, A.M、Bountra, C、Feller, S.M，以及结构基因组学联合体（Structural Genomics Consortium, SGC）
存档日期：2014-09-04
发布日期：2015-08-19
最后修改日期：2024-01-10
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.65埃（Å）
引用文献：《衔接蛋白CD2相关蛋白（CD2AP）的三个Src同源3（SH3）结构域的差异化识别偏好及其与Ras和Rab互作蛋白3（RIN3）的直接结合》，J. Biol. Chem., 290, 2015