Structure of unphosphorylated IRE1 in complex with G-1749
收藏Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Structure of unphosphorylated IRE1 in complex with G-1749 Descriptor: Serine/threonine-protein kinase/endoribonuclease IRE1, ethyl ~{N}-[6-methyl-5-[3-[2-[[(3~{S})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]carbamate Authors: Ferri, E, Wang, W, Joachim, R, Mortara, K. Deposit date: 2020-03-09 Release date: 2020-12-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.736 Å) Cite: Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands. Nat Commun, 11, 2020
创建时间：
2020-03-09
