Human Butyrylcholinesterase in complex with 2-(N-hydroxyimino)-N-[(1S)-3-{4-[(2-methyl-1H-imidazol-1-yl)methyl]-1H-1,2,3-triazol-1-yl}-1- phenylpropyl]acetamide

Human Butyrylcholinesterase in complex with 2-(N-hydroxyimino)-N-[(1S)-3-{4-[(2-methyl-1H-imidazol-1-yl)methyl]-1H-1,2,3-triazol-1-yl}-1- phenylpropyl]acetamide Descriptor: (2~{E})-2-hydroxyimino-~{N}-[(1~{S})-3-[4-[(2-methylimidazol-1-yl)methyl]-1,2,3-triazol-1-yl]-1-phenyl-propyl]ethanamid e, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(5-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Brazzolotto, X, Sinko, G, Marakovic, N, Knezevic, A. Deposit date: 2019-10-28 Release date: 2020-07-15 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Enantioseparation, in vitro testing, and structural characterization of triple-binding reactivators of organophosphate-inhibited cholinesterases. Biochem.J., 477, 2020

与2-(N-羟基亚氨基)-N-[(1S)-3-{4-[(2-甲基-1H-咪唑-1-基)甲基]-1H-1,2,3-三唑-1-基}-1-苯丙基]乙酰胺结合的人类丁酰胆碱酯酶（Butyrylcholinesterase）
Descriptor: 描述符：(2E)-2-羟基亚氨基-N-[(1S)-3-[4-[(2-甲基咪唑-1-基)甲基]-1,2,3-三唑-1-基]-1-苯基丙基]乙酰胺、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-[α-L-吡喃岩藻糖-(5→6)]2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖……
Authors: 作者：Brazzolotto, X、Sinko, G、Marakovic, N、Knezevic, A.
Deposit date: 入库日期：2019-10-28
Release date: 发布日期：2020-07-15
Last modified: 最后修改日期：2024-11-06
Method: 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.7埃（Å）
Cite: 引用文献：《有机磷抑制的胆碱酯酶三重结合再激活剂的对映分离、体外测试及结构表征》，《生物化学杂志》（Biochem. J.），477，2020年