Summary fMRI and physiology data from Valsalva maneuver in female and male healthy subjects

This dataset includes summary physiology and MRI data used in a publication identifying sex differences in insular organization to an autonomic challenge, the Valsalva maneuver. The protocol consisted of healthy participants performing a series of four 18-second Valsalva maneuvers one minute apart, with baseline and recovery periods. Continuous fMRI whole-brain scans were collected at 2 s intervals, and concurrent pulse oximetry data were acquired. The data include the SaO2 levels and continuous heart rate derived from the pleth waveform. The files include pdf and MATLAB figures, and tables and results from a SAS dataset with statistical results from RMANOVA (see 10.12688/f1000research.8252.1 for method). The MRI data include summary T1 files after DARTEL normalization in SPM12. The fMRI data include the preprocessing whole-brain images (motion-corrected, coregistered to T1, spatially normalized using T1 DARTEL parameters, smoothed 8mm FWHM), and VOI-specific timetrends, figures and RMANOVA statistics and graphs. Full details are included in the publication (10.3389/fneur.2016.00087).