Additional file 1: of Pharmacological inhibition of ABCC3 slows tumour progression in animal models of pancreatic cancer
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Figure S1. MCI-715- a specific inhibitor of ABCC3. Figure S2. Pharmacological inhibition of ABCC3 with MCI-715 reduces the activity of pSTAT3 Y705 and HIF1Îą. Figure S3. MCI-715 treatment in the animal models of PDAC. Figure S4. MCI-715 treatment induces apoptosis in the KPC primary cell line. Figure S5. Modulation of ABCC3 activity influences the viability of epithelial and stromal PDAC cells. (ZIP 4873 kb)
补充图S1. MCI-715——ABCC3的特异性抑制剂。 补充图S2. 利用MCI-715对ABCC3进行药理学抑制可降低pSTAT3 Y705与HIF1α的活性。 补充图S3. MCI-715处理在胰腺导管腺癌（PDAC）动物模型中的应用。 补充图S4. MCI-715处理可诱导KPC原代细胞系发生凋亡。 补充图S5. 调控ABCC3活性可影响上皮细胞与基质型胰腺导管腺癌（PDAC）细胞的存活能力。（ZIP 4873 kb）
创建时间：
2023-06-28
