Gene sets and associated p-values that are differentially expressed (T-ALL versus Healthy) using Gene Expression Omnibus Accession GSE46170 and a False Discovery Rate of.0025.

Individual genes within each set can be found at software.broadinstitute.org/gsea/msigdb [2]. Individual gene p-values are computed with the Wilcoxon rank-sum test. Gene sets identified with an asterisk (*) were also identified by Stouffer’s method. Description of gene sets in Table 7 taken from Subramanian et al. [2]. 1. “Deregulation of CDK5 in Alzheimers Disease” 2. “Genes involved in Pre-NOTCH Transcription and Translation” 3. “Genes involved in Regulation of Complement cascade” 4. “Genes involved in p38MAPK events” 5. “Oxidative Stress Induced Gene Expression Via Nrf2” 6. “Genes involved in Signaling by BMP” 7. “Genes involved in Elevation of cytosolic Ca2+ levels” 8. “Genes up-regulated during formation of blood vessels (angiogenesis)” 9. “Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)”.