AIS_WES_001
收藏NIAID Data Ecosystem2026-03-13 收录
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https://www.omicsdi.org/dataset/node/OEX00001674
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资源简介：
Adolescent idiopathic scoliosis AIS represented the majority of scoliotic disorders with an approximately 5 incidence rate. However the etiology of AIS remains poorly understood. Recent progresses suggested that AIS is a complex polygenic disease with large genetic and phenotypic heterogeneity. Therefore additional genetic researches were needed to expand the genomic architecture of AIS. The whole exome sequencing project is including 195 AIS samples to investigate the distribution of rare AIS-associated variants. Additionally severity-correlated genetic factors and phenotype-genotype associations were determined by comparing the different subgroups of AIS defined by clinical manifestations.
创建时间：
2021-12-28
