Cryo-EM Structure of the Prostaglandin E2 Receptor 4 Coupled to G Protein
收藏Protein Data Bank Japan2024-11-06 更新2026-06-30 收录
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Cryo-EM Structure of the Prostaglandin E2 Receptor 4 Coupled to G Protein Descriptor: (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... Authors: Huang, S.M, Xiong, M.Y, Liu, L, Mu, J, Sheng, C, Sun, J. Deposit date: 2023-03-02 Release date: 2024-01-03 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Single hormone or synthetic agonist induces G s /G i coupling selectivity of EP receptors via distinct binding modes and propagating paths. Proc.Natl.Acad.Sci.USA, 120, 2023
创建时间:
2023-03-02



