IGHV and TRB immune repertoire sequencing data from A20 haploinsufficiency and healthy humans.. IGHV and TRB immune repertoire sequencing data from A20 haploinsufficiency and healthy humans.
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https://www.ncbi.nlm.nih.gov/bioproject/PRJEB58966
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资源简介：
Genetic TNFAIP3 (A20) inactivation is a classical somatic lymphoma lesion and the genomic trait in haploinsufficiency of A20 (HA20). In a cohort of 33 HA20 patients, we show that heterozygous TNFAIP3 loss skews immune repertoires towards lymphocytes with classical self-reactive antigen receptors typically found in B and T cell lymphomas.
创建时间：
2023-07-28
