Research on Inhibiting the BLM Helicase in Goat Oocytes

NIAID Data Ecosystem2026-05-10 收录

山羊卵母细胞发育

减数分裂调控

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP593628 数据链接链接失效反馈

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Our study investigates the critical role of BLM helicase in goat oocyte maturation, revealing its essential functions in DNA repair, organelle homeostasis, and meiotic progression.

创建时间：

2026-01-11

Dot1-Dependent Histone H3K79 Methylation Promotes Activation of the Mek1 Meiotic Checkpoint Effector Kinase by Regulating the Hop1 Adaptor

减数分裂调控

组蛋白修饰

During meiosis, accurate chromosome segregation relies on the proper interaction between homologous chromosomes, including synapsis and recombination. The meiotic recombination checkpoint is a quality

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PRDM9 methyltransferase is essential for meiotic DSB formation. PRDM9 methyltransferase is essential for meiotic DSB formation

减数分裂调控

表观遗传修饰

The programmed formation of hundreds DNA double strand breaks (DSBs) is essential for proper meiosis and fertility. In mice and humans, the location of these breaks is determined by the meiosis-specif

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Meiotic time course of the trimethylation of the Lysine 4 of Histone H3 (H3K4me3) in a mutant clb5Delta-clb6Delta. Saccharomyces cerevisiae

表观遗传修饰

减数分裂调控

To study the meiotic dynamic of the methylation of H3K4, in relation with the transcriptomic regulation, we determine the meiotic time-course of H3K4me3 by ChIP-chip in a mutant deficient for DSB form

NIAID Data Ecosystem20

Characterization of ZFP541's occupency sites on genome in pachytene and diplotene spermatocytes. Characterization of ZFP541's occupency sites on genome in pachytene and diplotene spermatocytes

减数分裂调控

生殖细胞表观遗传学

The DSB-machinery, which induces the programmed DNA double-strand breaks (DSBs) in leptotene and zygotene stages during meiosis, needs to be kept in silence after the initiation of pachytene stage to

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Bifunctional snoRNA snr107 in gametogenesis S.pombe

非编码RNA功能

减数分裂调控

Small nucleolar RNAs (snoRNAs) are non-coding transcripts that guide chemical modifications of RNA substrates and contribute to gene expression at the epigenetic and post-transcriptional levels. Howev

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Research on Inhibiting the BLM Helicase in Goat Oocytes

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