Copper-Catalyzed Oxidative Trifunctionalization of Olefins: An Access to Functionalized β‑Keto Thiosulfones

Aerobic
oxidative trifunctionalization of olefins for the synthesis
of functionalized β-keto thiosulfones has been described. The
transformation proceeds through molecular oxygen activation under
copper catalysis and forms the two new C–S bonds in a single
operation using mild conditions. A novel Cu-catalyzed sulfonyl radical
addition/oxidation/funtionalization relay mechanism was proposed for
the discovered reaction.