Complete atrio-ventricular canal defects in mouse hearts lacking G-protein receptor kinases. Mus musculus
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA344339
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资源简介：
Combined ablation of all 3 cardiac-expressed GRKs in the developing mouse heart impaired Hedgehog/Smoothened and GATA signaling, recapitulating heart abnormalities of human Complete Atrioventricular Septal Defect. Overall design: Cardiac transcriptomes from mouse E13.5 hearts (8 wt, 8 haploinsufficient GRK2+/-GRK5-/-GRK6-/- and 7 GRK-triple knockout GRK2-/-GRK5-/-GRK6-/-) were generated via Illumina RiboZeroGold rRNA depletion and subsequent single-end 50 nt sequencing on Illumina HiSeq 2500
创建时间：
2016-09-23
