Insulin receptor kinase complexed with an inhibitor
收藏Protein Data Bank Japan2023-08-30 更新2026-03-21 收录
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Insulin receptor kinase complexed with an inhibitor Descriptor: 2-[(2-{[1-(N,N-dimethylglycyl)-5-methoxy-1H-indol-6-yl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-6-fluoro-N-methylbenzamide, Insulin receptor Authors: Chamberlain, S, Atkins, C, Deanda, F, Dumble, M, Gerding, R, Groy, A, Korenchuk, S, Kumar, R, Lei, H, Mook, R, Moorthy, G, Redman, A, Rowland, J, Sabbatini, P, Shewchuk, L. Deposit date: 2008-09-19 Release date: 2008-12-23 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase. Bioorg.Med.Chem.Lett., 19, 2009
创建时间：
2008-09-19
