Dataset for Transmembrane Fluoride Transport: Direct Measurement and Selectivity Studies

Data supporting:
Clarke, Harriet et al (2016) Transmembrane Fluoride Transport: Direct Measurement and Selectivity Studies. Journal of the American Chemical Society.

Fluoride has been overlooked as a target in the development of synthetic anion transporters despite natural fluoride transport channels being recently discovered. In this paper we report the direct measurement of fluoride bilayer transport facilitated by a series of strapped calix[4]pyrroles and show that these compounds facilitate transport via an electrogenic mechanism (determined using valinomycin and monensin coupled transport assays and an additional osmotic response assay). An HPTS transport assay was used to quantify this electrogenic process and assess the inter-ference of naturally occurring fatty acids with the transport process and Cl- over H+/OH- transport selectivity