首页/数据集/The CNS-Heart Axis is a Source of Cardiac Dysfunction in Mouse Models of Huntington's Disease

The CNS-Heart Axis is a Source of Cardiac Dysfunction in Mouse Models of Huntington's Disease

ChEBI2014-07-15 更新2026-07-21 收录

亨廷顿病模型

神经心脏病理学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-58996 数据链接链接失效反馈

官方服务：

资源简介：

The CNS-Heart Axis is a Source of Cardiac Dysfunction in Mouse Models of Huntington's Disease

应用场景：

创建时间：

2014-07-15

亨廷顿病模型

神经元基因表达

Primary neuron model of Huntington's Disease. 2 treatment groups: A) Infected 4 weeks prior with TRE-Htt-N853-18Q-expressing recombinant lentivirus, B) Infected 4 weeks prior with TRE-Htt-N853-82Q-exp

NIAID Data Ecosystem70

RNA-sequencing of brain microvascular endothelial cell dysfunction in an isogenic juvenile iPSC model of Huntington's disease

亨廷顿病模型

血脑屏障转录组学

Huntington's disease (HD) is associated with dysfunction of the blood-brain barrier, including brain microvasscular endothelial cells (BMECs). We report changes in gene expression of induced pluripote

NIAID Data Ecosystem40

Autophagy gene expression in rAAV-htt853 injected mice.

自噬基因表达

亨廷顿病模型

Selected autophagy markers were analyzed by qRT-PCR in hypothalamic tissue from mice injected with rAAV5-htt853-79Q or rAAV5-htt853-18Q and uninjected controls, 8 weeks post injection (n = 7/group). T

Figshare2015-12-02 更新30

Euploid HD iPSC lines (e.g. lines with a normal karyotype when first generated) accumulate abnormalities at the same rate as euploid control lines.

干细胞遗传稳定性

亨廷顿病模型

Euploid HD iPSC lines (e.g. lines with a normal karyotype when first generated) accumulate abnormalities at the same rate as euploid control lines.

NIAID Data Ecosystem60

Time course of total CD200 gene expression in the neocortex, hippocampus, and striatum of R6/1 mice.

亨廷顿病模型

基因表达

Time course of total CD200 gene expression in the neocortex, hippocampus, and striatum of R6/1 mice.

NIAID Data Ecosystem40