Human placental tissues:control group vs non-diabetic fetal macrosomia (NDFMS) group

To investigate whether aberrant lncRNA expression in the placenta is involved in the pathogenesis of NDFMS and to elucidate its biological mechanisms. The expression profile of lncRNAs in the placentas of pregnant women with NDFMS was investigated using an Agilent Human LncRNA Microarray. Differentially expressed lncRNAs were selected for validation using reverse transcription-quantitative polymerase chain reaction (RT-qPCR). eight samples from the NDFMS group and eight samples from the control group were prepared into two merged RNA samples, one per each group, for microarray screening. RNA labeling and microarray hybridization were performed