Summary of high-throughput sequencing parameters.

#number of quality sequences obtained for a given sample.
*number of observed operational taxonomic units.
**Shannon diversity index.
$Good’s coverage; C = 1 n1/N, where n1 is the number of OTUs that have been sampled once, and N is the total number of sequences.
†Calculated with Mothur at the 3% distance level. Values in brackets are 95% confidence intervals as calculated by Mothur.
∧For subjects who underwent colonoscopy: −1m, −1w, sample obtained one month, one week pre-colonoscopy, +1w, +1m, +3m, sample obtained 1 week, one month, or 3–6 months post-colonoscopy, respectively. For subjects who did not undergo colonoscopy: +3m, sample obtained 3–6 months after the first sample.