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Crystal structure of PDE10A in complex with ASP9436

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Protein Data Bank Japan2024-03-20 更新2026-03-21 收录
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Crystal structure of PDE10A in complex with ASP9436 Descriptor: 1-methyl-5-(1-methyl-3-{[4-(1-methyl-1H-benzimidazol-4-yl)phenoxy]methyl}-1H-pyrazol-4-yl)pyridin-2(1H)-one, MAGNESIUM ION, ZINC ION, ... Authors: Amano, Y, Honbou, K. Deposit date: 2015-02-02 Release date: 2015-06-17 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.03 Å) Cite: Addressing phototoxicity observed in a novel series of biaryl derivatives: Discovery of potent, selective and orally active phosphodiesterase 10A inhibitor ASP9436 Bioorg.Med.Chem., 23, 2015
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2015-02-02
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