Human Long Intergenic Noncoding RNA Linc-ADAL Knockdown in Mature Adipocytes using Lentiviral ShRNA
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE95173
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资源简介：
Thousands of human long intergenic noncoding RNAs (lincRNAs) have been detected in human adipose tissue. Here we characterized the function of one human adipse lincRNA, linc-ADAL (chr5:115292235-115296985) in mature adipcoytes through loss-of-function studies. Our results indicate that knockdown of linc-ADAL in differentiated adipocytes modulated expression of lipid metabolism genes. Lentiviral based shRNAs were used to knockdown linc-ADAL in differentiated ASC-derived adipocytes. ASC-adipoctes were transduced on day 8 of adipogenic differentiation. Cells were harvested for RNA extraction on day 6 post-transduction.
创建时间：
2019-05-15
