Haplotype frequencies of four polymorphisms examined in RAGE gene between patients and controls and their risk prediction for coronary artery disease.

Abbreviations: CAD, coronary artery disease, PSim, simulated P value; OR, odds ratio; 95% CI, 95% confidence interval. PSim was calculated based on randomly permuting the trait and covariates and then computing the haplotype score statistics. *Alleles in haplotype were presented in order of polymorphisms rs1800625, rs1800624, rs2070600 and rs184003. †OR, 95% CI, and P values were calculated after considering age, gender, body mass index, systolic blood pressure, and fasting glucose as covariates.