Additional file 5: Figure S2. of Guanylate-binding protein-1 is a potential new therapeutic target for triple-negative breast cancer

Analysis of TNBC versus non-TNBC and TNBC versus normal DE genes from the TCGA samples. Volcano plot of the FC of the genes TNBC versus non-TNBC (A) and TNBC versus normal (B) comparisons. Non-DE (or DE but with a p-value >0.05) genes are indicated with gray circles, while DE genes are indicated with blue circles when downregulated and red circles when upregulated. Genes showing an FC ≥ +2 and FC ≤ −2, with an FDR ≥ 0.05, were considered up- and downregulated, respectively. The numbers outside the circles refer to all genes that passed the FDR cutoff, while the numbers inside the circles are DE genes that passed both the FDR and fold-change cutoffs. Principal component analysis using DE genes obtained from TNBC versus non-TNBC (C) and TNBC versus normal tissues (D) comparisons. PCA correlations are denoted with circles around the samples (XLS 2112 kb)