Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE162168
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We present evidence of mechanistically diverse allosteric relays converging on a few peptidyltransferase center (PTC) nucleotides, and propose a general model of antibiotic resistance mediated by these ARE-ABCFs E. faecalis cell lysate and RqcH 50s-bound (i.e. immunopreciptated, RqcH 50s-IP) tRNAs used for tRNA microarrays to measure tRNA abundance – 2 biological replicates in total; 2 – RqcH 50s-IP and 1 - total tRNA (lysate)
创建时间：
2021-06-16
