All celluar and molecular biology source data and materials
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All source data and materials of cellular function and molecular biology assays to demonstrate FAK/SFK axis-mediated the tyrosine phosphorylation of ACLY and ALDOA to induce the downstream reprogram, including facilitating CDK7/9-mediated the expression of MCMs/CDC45 complex in primary tumor cells, and stimulating transcriptional activity of Yamanaka factors to induce the expression of cell plasticity-related molecules in metastatic lymph nodes. Resultantly, FAK/SFK axis-phosphorylated ACLY and ALDOA induce the lymph node metastasis of ESCC cells.
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figshare创建时间:
2025-08-14



