comparison of primary epicardium explant derived CDCs and primary Epicardial cells. comparison of primary epicardium explant derived CDCs and primary Epicardial cells

The analysis showed differences of transcriptomes between primary epicardium explant derived CDCs and primary Epicardial cells directly isolated from the heart epicardium.SB-431542 was an effective TGF-b pathway inhibitor that could obviously inhibit the epicardial cells Epithelial-mesenchymal transition. SB-432542 treatment could produce some epithelial clones in the CDCs,which showed epicardiac specific expression profile, compared with the CDCs. Overall design: primary CDCs, primary Epicardial cells and SB-431542 induced epithelial clone-1 mRNA profiles were generated by deep sequencing, in triplicate, using BGIseq500 platform.