Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE83243
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We isolated RNAs from Otp-lineage cells in the mouse brain using translating ribosome affinity purification (TRAP) approach. We compared two groups of mice: Otp-cre; ROSAfsTRAP (control) and Otp-cre; Cicf/f; ROSAfsTRAP (conditional knockout). Following RNA isolation, RNAseq was performed and gene expression profiles were compared between controls and conditional knockouts. Examination of gene expression in Otp-lineage neurons in two mouse groups.
创建时间：
2019-05-15
