Major signaling pathways affecting the fate of stem cells during ocular tissue injury and repair. Mus musculus

we designed and selected small molecule compounds targeting these key signaling pathway nodes to specifically regulate dedifferentiation/dedifferentiation of ocular cell signaling pathways and ocular histopathology after injury, reverse cell repair, and promote their structure and function change. The regenerative direction was developed to achieve the self-healing effect of the cornea and retina. Our research results of this subject are expected to clarify the signaling pathways of corneal epithelial cells and retinal Muller cell transdifferentiation/dedifferentiation in the process of eye tissue injury repair and the mechanism of their influence on tissue regeneration