Cellular aging can be monitored by DNA-methylation changes at specific CpG sites
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE29661
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资源简介：
Long-term culture associated changes need to be considered for quality control of cell preparations – especially in cellular therapy. Here we describe a simple method to track cellular aging based on continuous DNA-methylation changes at six specific CpG sites. This epigenetic signature can be used as a biomarker for various cell types to predict the state of cellular aging with regard to the number of passages or days of in vitro culture. 8 samples of human dermal fibroblasts. 4 samples of mesenchymal stem cells (MSC) from human adipose tissue.
创建时间：
2015-01-02
