Results of pulse wave analysis performed in hemodialysis patients and healthy subjects

Two standard hemodialysis (HD) sessions were monitored in 35 anuric, prevalent hemodialysis patients. At the time of the study none of the patients had diagnosed cardiovascular disease. All patients underwent their regular treatment with ultrafiltration volume set to achieve patient-specific post-disalytic dry weight . All patients had arteriovenous fistulas. We enrolled an additional group of 32 healthy volunteers (control group) in order to investigate further the differences between HD and general population. The only enrollment criterion for this group was lack of any diagnosed cardiovascular disease. Participants were enrolled from June 2014 through February 2018. Pulse wave shape in radial artery was recorded using applanation tonometry (SphygmoCor, AtCor Medical, Australia) once in healthy individuals and about 15 minutes before start, after start, before end, and after end of two hemodialysis sessions performed in dialysis patients after 3- and 2-day interdialytic intervals.All recordings were performed by one trained clinician with measurement performed in the non-fistula arm in the case of hemodialysis patients. The radial pulse wave was calibrated to the blood pressure measured oscillometrically at brachial artery (Omron M3, Omron Healthcare, Kyoto, Japan). Data is presented using proprietary SphygmoCor output format.