Biological General Repository for Interaction Datasets

The Biological General Repository for Interaction Datasets (BioGRID) is a public database that archives and disseminates genetic and protein interaction data from model organisms and humans. BioGRID currently holds over 1,740,000 interactions curated from both high-throughput datasets and individual focused studies, as derived from over 70,000+ publications in the primary literature. Complete coverage of the entire literature is maintained for budding yeast (S. cerevisiae), fission yeast (S. pombe) and thale cress (A. thaliana), and efforts to expand curation across multiple metazoan species are underway. All data are freely provided via our search index and available for download in many standardized formats.生物交互数据集通用存储库（The Biological General Repository for Interaction Datasets，简称BioGRID）是一款公开数据库，用于归档并传播模式生物与人类的遗传及蛋白质交互数据。目前BioGRID收录了超过174万条交互数据，这些数据均从高通量数据集与针对性个体研究中甄选整理而来，其来源涵盖逾7万篇原始文献。该库已对酿酒酵母（S. cerevisiae）、裂殖酵母（S. pombe）以及拟南芥（A. thaliana）的全部相关文献实现完整覆盖，当前正推进针对多类后生动物物种的整理覆盖工作。所有数据均可通过本库的搜索索引免费获取，并支持以多种标准化格式下载。

搜集汇总

背景与挑战

背景概述

BioGRID是一个公开的生物医学交互数据库，专门收集和整理基因、蛋白质及化学相互作用数据，覆盖人类和多种模式生物。该数据库基于大量科学文献的全面整理，提供超过数百万条交互记录，并可通过标准化格式免费访问和下载。