five

RAP proteins regulate apicoplast noncoding RNA processing in Plasmodium falciparum

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP523984
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资源简介:
We demonstrated that PfRAP03 (PF3D7_0518100) and PfRAP08 (PF3D7_0707800) are essential apicoplast proteins. Transcriptomics and proteomics, including high-throughput sequencing of RNA isolated by crosslinking immunoprecipitation (eCLIP-seq), confirmed their involvement in RNA biology and binding to apicoplast tRNAs and rRNAs, thus validating their role in post-transcriptional regulation in this parasite-specific organelle.
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2025-05-14
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